There are three hardcoded drug types, these are Rohypnol, Vampire Blood, and Poison. There are also many recreational drugs, both prescription and street. Recreational drugs send a message when taken and have the power to inflict a temporary level one imprint.
The hardcoded drugs can be either taken by drinking them, or put into a drink or food object. To dose a drink or meal with a drug, use pour (drug) (drink/food)
Poison when taken will have no immediate noticeable effect. It will take between 20-30 minutes to affect a normal person, about double that for a supernatural. Vampires are immune to poison. When the effect kicks in the victim will be wounded and weakened, regeneration will not help them heal this wound. If someone logs off before the poison has kicked in, it will kick in when they next log on.
Rohypnol when taken will have no noticeable or immediate effect. It will take 20-30 minutes to effect a normal person, about double that for a supernatural or three times for a vampire. When the effect kicks in the victim will pass out, rendering them helpless and able to be tied up, dragged around etc. If someone logs off before the drug kicks in they will pass out then, disconnected but with their character remaining in the game in the same way as if they'd been abducted. You can use the tuckin command to send a character in this state off the game.
Please check the Vampires page for information on Vampire Blood.